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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus?

Figure 4

Infiltration of T cells and macrophages into the papillary dermis and epidermis. (a) Percentage of CD3 staining in the dermis before and after irradiation in 15 patients with systemic lupus erythematosus (SLE) and 12 controls and in 20 lupus erythematosus (LE) biopsies quantified by morphometry. (b) Percentage of CD68 staining in the dermis before and after irradiation in 15 patients with SLE and 12 controls and in 20 LE biopsies quantified by morphometry. (c) Percentage of CD3 staining in the epidermis before and after irradiation comparing patients with infiltrates (n = 5), patients without infiltrates (n = 10), and controls (n = 13) and in 20 LE biopsies. (d) Percentage of CD68 staining in the epidermis before and after irradiation comparing patients with infiltrates (n = 5), patients without infiltrates (n = 10), and controls (n = 13) and in 20 LE biopsies. Median value is indicated by a horizontal line. ■, patients with infiltrates (IP); , patients without infiltrates (P); , controls (C). *p < 0.05, **p < 0.01, ***p ≤ 0.001. UVB, ultraviolet B light.

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