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Table 2 Characteristics of patients included in the LE skin biopsies: cumulative ACR criteria, autoantibody specificities, and medication

From: Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus?

Patient characteristics
SBC/co-loc No. Gender Age      A C R      Prednisone Hydroxychloroquine Azathioprine Autoantibody
    (Years) 1 2 3 4 5 6 7 8 9 10 11 (mg/day) (mg/day) (mg/day) specificities
+/+ 1 F 45 - - - - - + + - - + +   - 75 SSA/SSB/dsDNA
+/+ 2 F 51 + - + - - + - - + - + 5 - 100 SSA/SSB
+/+ 3 F 70 - + - - - - - - + + + 10 200 25 Sm/SSA/nRNP
-/- 4 M 47 - + + - - - - - +   + - - - SSA/SSB
-/- 5 F 45 + + - + + - - - + + + - 5 - Sm/nRNP/CL
+/- 6 F 50 + + - + + - - - + + + 12.5 600 - Sm/nRNP/CL
+/+ 7 F 49 + + - + + - - - + + + 10 600 - Sm/nRNP/CL
+/- 8 F 39 + - + + + - - - - + + 60 - - dsDNA
+/+ 9 F 41 + - - - + + - - - + + 2.5 - 75 SSA/SSB/dsDNA
+/+ 10 F 45 - + - - + + + - + + + 5 400 - dsDNA
+/+ 11 F 46 - + - - + + + - + + + 5 400 - dsDNA
+/- 12 F 38 - + - - + - - - - + + - - - dsDNA
-/- 13 F 75 - - - - + - - - + + + - - - dsDNA/CL
+/- 14 F 33 + - - - + - - - + + + - - - SSA/Sm/nRNP/dsDNA
+/+ 15 F 58 - + + - - - - - + + + - - - SSA/dsDNA
+/- 16 F 38 - + + - - - - - + + + - - - SSA/dsDNA
-/- 17 F 49 - + + - - - + - + - + - 800 - dsDNA/CL
+/+ 18 F 49 - + - + + + - - + + + 7.5 - - dsDNA
+/+ 19 M 35 - + + - - - - -   + + - - - SSA/dsDNA
+/- 20 F 26 + - + - - - - - + + + - - - nRNP/Sm/dsDNA
  1. ACR criteria numbered according to Bombardier et al. [19]: 1, malar (or 'butterfly') rash; 2, discoid rash; 3, sensitivity to light, or photosensitivity; 4, oral ulcers; 5, arthritis; 6, serositis; 7, kidney disorder; 8, neurologic disorder; 9, blood abnormalities; 10, positive antiphospholipid antibody test; 11, immunologic disorder, including lupus anticoagulant, positive anti-double-stranded DNA, false-positive syphilis test, or positive anti-Smith test (such as anticardiolipin). + and - indicate cumulative presence or absence, respectively, of a particular criterion. In the leftmost column, +/- indicates biopsies containing SBCs but no apparent co-localisation, +/+ indicates biopsies containing co-localisation of inflammatory lesions and SBCs, and - indicates biopsies without SBCs. ACR, American College of Rheumatology; co-loc, co-localisation; F, female, LE, lupus erythematosus; M, male; SBC, sunburn cell; UVB, ultraviolet B light.