Graph illustrating the means and 95% confidence intervals (CIs) of the gene expression profiles. To normalise values, the mean of each control group has been used to normalise and produce fold changes in expression. The results of the COL9A3 transcript are omitted because the 95% CIs were very high. *Significant difference. BGN, biglycan; COL1A2, type I collagen, alpha two chain; COL2A1, type II collagen alpha 1 chain; COL3A1, type III collagen alpha 1 chain; COL5A1, type V collagen alpha 1 chain; COL9A3, type IX collagen alpha 3 chain; CSPG2, chondroitin sulphate proteoglycan 2; CTSD, cathepsin D; D, disease; LUM, lumican; MMP13, matrix metalloproteinase 13; N, normal; TIMP1, tissue inhibitor of metalloproteinase 1.