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Table 3 Correlation between α-actinin-binding antibody levels and clinical findings in patients with SLE

From: Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis

Disease feature Spearman's rho p value
Anti-dsDNA Ab ELISA (IU/ml) 0.638 0.0001a
Anti-dsDNA Ab EliA (IU/ml) 0.601 0.0001a
Total SLEDAI score 0.378 0.0001a
ESR 0.254 0.035
CRP (mg/l) 0.236 0.048
C3 (mg/l) -0.102 0.522
C4 (mg/l) -0.078 0.623
Age (years) -0.197 0.051
Creatinin clearance (ml/minute) 0.339 0.199
Proteinuria (g/24 hours) 0.182 0.484
Renal SLICC score -0.031 0.796
Total SLICC -0.385 0.0053
  1. aSignificant results (p < 0.005) after the Bonferroni correction. C3, complement factor 3; C4, complement factor 4; CRP, C-reactive protein; EliA, fluorescence enzyme immunoassay test for anti-double-stranded DNA (Phadia GmbH); ELISA, enzyme-linked immunosorbent assay; ESR, erythrocyte sedimentation rate; SLE, systemic lupus erythematosus; SLEDAI, Systemic Lupus Erythematosus Disease activity index; SLICC, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for systemic lupus erythematosus.