Skip to main content

Advertisement

Table 4 Multivariate models building on all significant factors in univariate analysis

From: Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis

Model Feature Unstandardised coefficients (B) Standard error Standardised coefficients beta t p value
1 (Constant) 74.907 23.552   3.180 0.003
  Anti-dsDNA (ELISA) Ab (U/ml) 0.413 0.149 0.381 2.765 0.008
2 (Constant) 72.028 23.730   3.035 0.004
  Anti-dsDNA (ELISA) Ab (U/ml) 0.520 0.184 0.480 2.828 0.007
  Anti-dsDNA Ab – EliA (IU/ml) -0.142 0.142 -0.169 -0.997 0.324
3 (Constant) 68.464 26.533   2.580 0.013
  Anti-dsDNA (ELISA) Ab (U/ml) 0.512 0.187 0.472 2.732 0.009
  Anti-dsDNA Ab – EliA (IU/ml) -0.137 0.145 -0.163 -0.947 0.349
  Total SLEDAI score 1.153 3.676 0.044 0.314 0.755
4 (Constant) 63.596 31.159   2.041 0.048
  Anti-dsDNA (ELISA) Ab (U/ml) 0.506 0.190 0.467 2.658 0.011
  Anti-dsDNA Ab – EliA (IU/ml) -0.132 0.147 -0.158 -0.901 0.373
  Total SLEDAI score 1.013 3.743 0.039 0.271 0.788
  ESR (mm) 0.208 0.677 0.044 0.307 0.761
5 (Constant) 65.107 31.917   2.040 0.048
  Anti-dsDNA (ELISA) Ab (U/ml) 0.512 0.194 0.473 2.646 0.012
  Anti-dsDNA Ab – EliA (IU/ml) -0.133 0.149 -0.159 -0.897 0.375
  Total SLEDAI score 1.137 3.808 0.044 0.299 0.767
  ESR (mm) 2.558 × 10-03 0.922 0.005 0.028 0.978
  CRP (mg/l) 0.154 0.522 0.057 0.295 0.769
6 (Constant) 61.031 58.443   1.044 0.303
  Anti-dsDNA (ELISA) Ab (U/ml) 0.513 0.196 0.473 2.614 0.013
  Anti-dsDNA Ab – EliA (IU/ml) -0.128 0.164 -0.152 -0.780 0.440
  Total SLEDAI score 1.196 3.919 0.046 0.305 0.762
  ESR (mm) 8.484 × 10-03 0.956 0.002 0.009 0.993
  CRP (mg/l) 0.144 0.541 0.053 0.267 0.791
  Age 0.108 1.284 0.015 0.084 0.934
7 (Constant) 59.716 59.051   1.011 0.318
  Anti-dsDNA (ELISA) Ab (U/ml) 0.542 0.206 0.501 2.627 0.012
  Anti-DNA-EliA (IU/ml) -0.134 0.166 -0.160 -0.808 0.424
  Total SLEDAI score 1.772 4.116 0.068 0.430 0.669
  ESR (mm) -6.240 × 10-03 0.965 -0.001 -0.006 0.995
  CRP (mg/l) 0.144 0.546 0.053 0.264 0.794
  Age -0.193 1.425 -0.028 -0.135 0.893
  Total SLICC 5.964 11.773 0.095 0.507 0.615
  1. Ab, antibody; anti-dsDNA, anti-double-stranded DNA; CRP, C-reactive protein; EliA, fluorescence enzyme immunoassay test for anti-double-stranded DNA (Phadia GmbH); ELISA, enzyme-linked immunosorbent assay; ESR, erythrocyte sedimentation rate; SLEDAI, Systemic Lupus Erythematosus Disease activity index; SLICC, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for systemic lupus erythematosus.