Figure 5From: P5L mutation in Ank results in an increase in extracellular inorganic pyrophosphate during proliferation and nonmineralizing hypertrophy in stably transduced ATDC5 cellsLevamisole treatment of the P5L cell line increases elaboration of extracellular inorganic pyrophosphate. (a) Treatment of the P5L-transduced cell line with levamisole results in a dramatic reduction in alkaline phosphatase (AP) activity. (b) Treatment with levamisole increases extracellular inorganic pyrophosphate (ePPi) in P5L-transduced cells. n = 3; *P ≤ 0.05.Back to article page