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Table 3 Relative signal values of inflammatory genes significantly affected by IL-1 and/or glucosamine

From: Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1β

Gene Treatment group
  No glucosamine, no IL-1 Glucosamine, no IL-1 IL-1, no glucosamine Glucosamine with IL-1
Arginosuccinate synthetase 6.3 19.4 2247.3 267.2
β-Nerve growth factor 16.1 21.6 196.2 13.0
Bone morphogenetic protein 2 42.7 57.7 375.4 100.2
Bone morphogenetic protein 4 494.9 77.3 147.7 68.2
Bone morphogenetic protein 6 60.9 13.9 435.9 85.9
Bone morphogenetic protein 7 0.9 5.8 76.2 8.2
CCL3 (MIP-1a) - 0.1 690.7 2.6
CCL5 (RANTES) 2.1 2.7 310.1 8.1
CCL7 (MCP-3) 32.2 69.4 3076.0 662.8
CCL22 (MDC) 0.3 0.6 47.2 5.4
Cdc42 GTPase inhibiting protein 105.0 116.5 189.4 124.4
Colony-stimulating factor 1 126.9 51.1 307.8 140.8
Colony-stimulating factor 2 - 20.1 1210.7 17.6
Colony-stimulating factor 3 - 6.0 1253.7 6.5
CXCL1 (GROa) 168.2 36.6 1730.6 496.2
CXCL2 (GROb) - 37.5 2988.2 92.4
CXCL5 (LIX) 2.0 2.4 441.3 16.2
CXCL10 (IP-10) 10.7 8.1 74.4 15.6
CXCL11 (I-TAC) - - 110.2 3.4
CXCL12 (SDF-a/b) 122.8 5.9 88.7 10.9
Cyclooxygenase 1 184.0 593.4 192.2 493.1
Cyclooxygenase 2 61.9 117.0 3493.9 405.5
Cysteine knot superfamily 1 (bone morphogenetic protein antagonist 1) 460.4 308.6 2174.9 732.7
Cytokine-induced neutrophil chemoattractant-2 15.2 54.4 3466.1 624.2
Dual-specificity phosphatase 6 179.9 88.9 658.7 109.9
Endothelial PAS domain protein 1 69.9 38.0 208.9 52.2
Fibroblast growth factor 7 1294.4 1078.9 1318.9 1745.9
Fibroblast growth factor 9 12.0 29.5 155.7 26.7
Fibroblast growth factor receptor 1 605.2 653.7 329.3 638.5
I-κBα 126.9 81.7 1108.4 399.0
I-κBβ 55.6 96.6 298.2 139.2
I-κBγ (NF-κB p105 subunit) 124.2 107.9 471.2 163.6
Insulin-like growth factor binding protein 3 81.6 7.4 249.9 10.4
Insulin-like growth factor binding protein 5 174.4 569.0 737.8 229.5
IL-1α 1.5 3.2 175.3 4.5
IL-1β - 2.4 119.4 2.7
IL-6 57.3 53.4 1717.8 159.0
IL-11 - - 124.4 -
IL-13 receptor, α 1 174.8 144.5 337.4 148.0
IL-23α subunit p19 - - 766.5 -
Janus kinase 2 89.7 102.9 251.0 128.7
JunB proto oncogene 129.5 89.0 377.8 148.4
Mitogen-activated protein kinase phosphatase (CPG21) 19.1 47.5 300.2 52.3
Nitric oxide synthase 2 0.1 2.1 1033.9 66.1
Ornithine aminotransferase 1080.5 1125.0 868.6 1059.1
Ornithine decarboxylase antizyme inhibitor 322.1 239.4 336.9 186.6
Phospholipase A2, group 2A 175.5 44.7 2085.9 358.0
Phospholipase A2, group 4A 269.9 303.2 668.2 339.7
Phospholipase A2, group 5 44.0 18.2 260.7 66.7
Platelet-derived growth factor A 439.8 492.9 745.9 597.5
Prostaglandin E2 synthase 32.8 46.9 3845.8 183.7
Pyrroline-5-carboxylate 602.5 643.8 348.3 609.3
Rel-B 31.6 28.7 186.2 71.5
Small inducible cytokine A2 221.4 711.0 4835.8 2945.5
Small inducible cytokine A20 26.9 137.8 4206.1 1609.7
Solute carrier family 7 (cationic amino acid transporter), member 8 8.1 19.4 560.3 21.7
Sox-4 533.0 460.8 248.5 572.2
TNF-induced protein 6 119.8 49.3 262.3 71.1