Figure 5

The autoantibody titers to non-citrullinated and citrullinated F-actin capping protein α-1 subunit (CapZα-1) in the individual patients with rheumatoid arthritis. The patients were classified into four groups according to the reactive patterns. (a) The autoantibodies both to non-citrullinated and citrullinated CapZα-1 were negative (group A). (b) The autoantibodies to non-citrullinated CapZα-1 were negative, and the autoantibodies to citrullinated CapZα-1 were positive (group B). (c) The autoantibodies to non-citrullinated CapZα-1 were positive, and the autoantibodies to citrullinated CapZα-1 were further increased (group C). (d) The autoantibodies both to non-citrullinated and citrullinated CapZα-1 were positive with similar titers (group D).