TY - JOUR AU - Martel-Pelletier, J. PY - 1999 DA - 1999// TI - Pathophysiology of osteoarthritis JO - Osteoarthritis Cartilage VL - 7 UR - https://doi.org/10.1053/joca.1998.0214 DO - 10.1053/joca.1998.0214 ID - Martel-Pelletier1999 ER - TY - JOUR AU - Radin, E. L. AU - Paul, I. L. AU - Tolkoff, M. J. PY - 1970 DA - 1970// TI - Subchondral changes in patients with early degenerative joint disease JO - Arthritis Rheum VL - 13 UR - https://doi.org/10.1002/art.1780130406 DO - 10.1002/art.1780130406 ID - Radin1970 ER - TY - JOUR AU - Radin, E. L. AU - Rose, R. M. PY - 1986 DA - 1986// TI - Role of subchondral bone in the initiation and progression of cartilage damage JO - Clin Orthop VL - 213 ID - Radin1986 ER - TY - JOUR AU - Mansell, J. P. AU - Bailey, A. J. PY - 1998 DA - 1998// TI - Abnormal cancellous bone collagen metabolism in osteoarthritis JO - J Clin Invest VL - 101 UR - https://doi.org/10.1172/JCI867 DO - 10.1172/JCI867 ID - Mansell1998 ER - TY - JOUR AU - Mansell, J. P. AU - Tarlton, J. F. AU - Bailey, A. J. PY - 1997 DA - 1997// TI - Biochemical evidence for altered subchondral bone collagen metabolism in osteoarthritis of the hip JO - Br J Rheumatol VL - 36 UR - https://doi.org/10.1093/rheumatology/36.1.16 DO - 10.1093/rheumatology/36.1.16 ID - Mansell1997 ER - TY - JOUR AU - Hilal, G. AU - Martel-Pelletier, J. AU - Pelletier, J. P. AU - Duval, N. AU - Lajeunesse, D. PY - 1999 DA - 1999// TI - Abnormal regulation of urokinase plasminogen activator by insulin-like growth factor 1 in human osteoarthritic subchondral osteoblasts JO - Arthritis Rheum VL - 42 UR - https://doi.org/3.0.CO;2-N DO - 3.0.CO;2-N ID - Hilal1999 ER - TY - JOUR AU - Hilal, G. AU - Martel-Pelletier, J. AU - Pelletier, J. P. AU - Ranger, P. AU - Lajeunesse, D. PY - 1998 DA - 1998// TI - Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: Possible role in subchondral bone sclerosis JO - Arthritis Rheum VL - 41 UR - https://doi.org/3.0.CO;2-X DO - 3.0.CO;2-X ID - Hilal1998 ER - TY - JOUR AU - Hilal, G. AU - Massicotte, F. AU - Martel-Pelletier, J. AU - Fernandes, J. C. AU - Pelletier, J. P. AU - Lajeunesse, D. PY - 2001 DA - 2001// TI - Endogenous prostaglandin E2 and insulin-like growth factor 1 can modulate the levels of parathyroid hormone receptor in human osteoarthritic osteoblasts JO - J Bone Miner Res VL - 16 UR - https://doi.org/10.1359/jbmr.2001.16.4.713 DO - 10.1359/jbmr.2001.16.4.713 ID - Hilal2001 ER - TY - JOUR AU - Bailey, A. J. AU - Sims, T. J. AU - Knott, L. PY - 2002 DA - 2002// TI - Phenotypic expression of osteoblast collagen in osteoarthritic bone: production of type I homotrimer JO - Int J Biochem Cell Biol VL - 34 UR - https://doi.org/10.1016/S1357-2725(01)00107-8 DO - 10.1016/S1357-2725(01)00107-8 ID - Bailey2002 ER - TY - JOUR AU - Grynpas, M. D. AU - Alpert, B. AU - Katz, I. AU - Lieberman, I. AU - Pritzker, K. P. H. PY - 1991 DA - 1991// TI - Subchondral bone in osteoarthritis JO - Calcif Tissue Int VL - 49 UR - https://doi.org/10.1007/BF02555898 DO - 10.1007/BF02555898 ID - Grynpas1991 ER - TY - JOUR AU - Mkukuma, L. D. AU - Imrie, C. T. AU - Skakle, J. M. S. AU - Hukins, D. W. L. AU - Aspden, R. M. PY - 2005 DA - 2005// TI - Thermal stability and structure of cancellous bone mineral from the femoral head of patients with osteoarthritis or osteoporosis JO - Ann Rheum Dis VL - 64 UR - https://doi.org/10.1136/ard.2004.021329 DO - 10.1136/ard.2004.021329 ID - Mkukuma2005 ER - TY - JOUR AU - Westacott, C. I. AU - Webb, G. R. AU - Warnock, M. G. AU - Sims, J. V. AU - Elson, C. J. PY - 1997 DA - 1997// TI - Alteration of cartilage metabolism by cells from osteoarthritic bone JO - Arthritis Rheum VL - 40 UR - https://doi.org/3.0.CO;2-E DO - 3.0.CO;2-E ID - Westacott1997 ER - TY - JOUR AU - Buckland-Wright, C. PY - 2004 DA - 2004// TI - Subchondral bone changes in hand and knee osteoarthritis detected by radiography JO - Osteoarthritis Cartilage VL - 12 UR - https://doi.org/10.1016/j.joca.2003.09.007 DO - 10.1016/j.joca.2003.09.007 ID - Buckland-Wright2004 ER - TY - JOUR AU - Buckland-Wright, J. C. AU - Lynch, J. A. AU - Macfarlane, D. G. PY - 1996 DA - 1996// TI - Fractal signature analysis measures cancellous bone organisation in macroradiographs of patients with knee osteoarthritis JO - Ann Rheum Dis VL - 55 UR - https://doi.org/10.1136/ard.55.10.749 DO - 10.1136/ard.55.10.749 ID - Buckland-Wright1996 ER - TY - JOUR AU - Buckland-Wright, J. C. AU - Macfarlane, D. G. AU - Lynch, J. A. AU - Clark, B. PY - 1990 DA - 1990// TI - Quantitative microfocal radiographic assessment of progression in osteoarthritis of the hand JO - Arthritis Rheum VL - 33 UR - https://doi.org/10.1002/art.1780330107 DO - 10.1002/art.1780330107 ID - Buckland-Wright1990 ER - TY - JOUR AU - Combettes-Souverain, M. AU - Issad, T. PY - 1998 DA - 1998// TI - Molecular basis of insulin action JO - Diabetes Metab VL - 24 ID - Combettes-Souverain1998 ER - TY - JOUR AU - Yamauchi, K. AU - Pessin, J. E. PY - 1994 DA - 1994// TI - Insulin receptor substrate-1 (IRS1) and Shc compete for a limited pool of Grb2 in mediating insulin downstream signaling JO - J Biol Chem VL - 269 ID - Yamauchi1994 ER - TY - JOUR AU - Kosaki, A. AU - Yamada, K. AU - Suga, J. AU - Otaka, A. AU - Kuzuya, H. PY - 1998 DA - 1998// TI - 14-3-3beta protein associates with insulin receptor substrate 1 and decreases insulin-stimulated phosphatidylinositol 3'-kinase activity in 3T3L1 adipocytes JO - J Biol Chem VL - 273 UR - https://doi.org/10.1074/jbc.273.2.940 DO - 10.1074/jbc.273.2.940 ID - Kosaki1998 ER - TY - JOUR AU - Ogihara, T. AU - Isobe, T. AU - Ichimura, T. AU - Taoka, M. AU - Funaki, M. AU - Sakoda, H. AU - Onishi, Y. AU - Inukai, K. AU - Anai, M. AU - Fukushima, Y. PY - 1997 DA - 1997// TI - 14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.40.25267 DO - 10.1074/jbc.272.40.25267 ID - Ogihara1997 ER - TY - JOUR AU - Massicotte, F. AU - Lajeunesse, D. AU - Benderdour, M. AU - Pelletier, J. P. AU - Hilal, G. AU - Duval, N. AU - Martel-Pelletier, J. PY - 2002 DA - 2002// TI - Can altered production of interleukin 1β, interleukin-6, transforming growth factor-β and prostaglandin E(2) by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patients JO - Osteoarthritis Cartilage VL - 10 UR - https://doi.org/10.1053/joca.2002.0528 DO - 10.1053/joca.2002.0528 ID - Massicotte2002 ER - TY - JOUR AU - Altman, R. AU - Asch, E. AU - Bloch, D. AU - Bole, G. AU - Borenstein, D. AU - Brandt, K. AU - Christy, W. AU - Cooke, T. D. AU - Greenwald, R. AU - Hochberg, M. PY - 1986 DA - 1986// TI - Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee JO - Arthritis Rheum VL - 29 UR - https://doi.org/10.1002/art.1780290816 DO - 10.1002/art.1780290816 ID - Altman1986 ER - TY - JOUR AU - Lajeunesse, D. AU - Busque, L. AU - Ménard, P. AU - Brunette, M. G. AU - Bonny, Y. PY - 1996 DA - 1996// TI - Demonstration of an osteoblast defect in two cases of human malignant osteopetrosis: Correction of the phenotype after bone marrow transplant JO - J Clin Invest VL - 98 UR - https://doi.org/10.1172/JCI118984 DO - 10.1172/JCI118984 ID - Lajeunesse1996 ER - TY - JOUR AU - Lajeunesse, D. AU - Kiebzak, G. M. AU - Frondoza, C. AU - Sacktor, B. PY - 1991 DA - 1991// TI - Regulation of osteocalcin secretion by human primary bone cells and by the human osteosarcoma cell line MG-63 JO - Bone Mineral VL - 14 UR - https://doi.org/10.1016/0169-6009(91)90025-U DO - 10.1016/0169-6009(91)90025-U ID - Lajeunesse1991 ER - TY - JOUR AU - Smith, P. K. AU - Krohn, R. I. AU - Hermanson, G. T. AU - Mallia, A. K. AU - Gartner, F. H. AU - Provenzano, M. D. AU - Fujimoto, E. K. AU - Goeke, N. M. AU - Olson, B. J. AU - Klenk, D. C. PY - 1985 DA - 1985// TI - Measurement of protein using bicinchoninic acid JO - Anal Biochem VL - 150 UR - https://doi.org/10.1016/0003-2697(85)90442-7 DO - 10.1016/0003-2697(85)90442-7 ID - Smith1985 ER - TY - JOUR AU - Laemmli, U. K. PY - 1970 DA - 1970// TI - Cleavage of structure proteins during assembly of the head of the bacteriophage T4 JO - Nature VL - 227 UR - https://doi.org/10.1038/227680a0 DO - 10.1038/227680a0 ID - Laemmli1970 ER - TY - STD TI - NIH Image. [http://rsb.info.nih.gov/nih-image/] UR - http://rsb.info.nih.gov/nih-image/ ID - ref26 ER - TY - JOUR AU - Doré, S. AU - Abribat, T. AU - Rousseau, N. AU - Brazeau, P. AU - Tardif, G. AU - Di Battista, J. A. AU - Cloutier, J. M. AU - Pelletier, J. P. AU - Martel-Pelletier, J. PY - 1995 DA - 1995// TI - Increased insulin-like growth factor 1 production by human osteoarthritic chondrocytes is not dependent on growth hormone action JO - Arthritis Rheum VL - 38 UR - https://doi.org/10.1002/art.1780380319 DO - 10.1002/art.1780380319 ID - Doré1995 ER - TY - JOUR AU - McCullough, K. D. AU - Martindale, J. L. AU - Klotz, L. O. AU - Aw, T. Y. AU - Holbrook, N. J. PY - 2001 DA - 2001// TI - Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state JO - Mol Cell Biol VL - 21 UR - https://doi.org/10.1128/MCB.21.4.1249-1259.2001 DO - 10.1128/MCB.21.4.1249-1259.2001 ID - McCullough2001 ER - TY - JOUR AU - Mirowski, M. AU - Rozalski, M. AU - Krajewska, U. AU - Balcerczak, E. AU - Mlynarski, W. AU - Wierzbicki, R. PY - 2003 DA - 2003// TI - Induction of caspase 3 and modulation of some apoptotic genes in human acute promyelocytic leukemia HL-60 cells by carboplatin with amifostine JO - Pol J Pharmacol VL - 55 ID - Mirowski2003 ER - TY - JOUR AU - Razzouk, S. AU - Shapiro, I. M. PY - 2003 DA - 2003// TI - Detection of apoptotic gene expression in human osteoblast-like cells by cDNA microarrays JO - J Bone Miner Metab VL - 21 UR - https://doi.org/10.1007/s00774-003-0419-5 DO - 10.1007/s00774-003-0419-5 ID - Razzouk2003 ER - TY - JOUR AU - Martin, T. J. AU - Allan, E. H. AU - Fukumoto, S. PY - 1993 DA - 1993// TI - The plasminogen activator and inhibitor system in bone remodeling JO - Growth Regul VL - 3 ID - Martin1993 ER - TY - JOUR AU - Massicotte, F. AU - Fernandes, J. C. AU - Martel-Pelletier, J. AU - Pelletier, J. P. AU - Lajeunesse, D. PY - 2006 DA - 2006// TI - Modulation of insulin-like growth factor 1 levels in human osteoarthritic subchondral bone osteoblasts JO - Bone VL - 38 UR - https://doi.org/10.1016/j.bone.2005.09.007 DO - 10.1016/j.bone.2005.09.007 ID - Massicotte2006 ER - TY - JOUR AU - Byon, J. C. AU - Kenner, K. A. AU - Kusari, A. B. AU - Kusari, J. PY - 1997 DA - 1997// TI - Regulation of growth factor-induced signaling by protein-tyrosine-phosphatases JO - Proc Soc Exp Biol Med VL - 216 UR - https://doi.org/10.3181/00379727-216-44153 DO - 10.3181/00379727-216-44153 ID - Byon1997 ER - TY - JOUR AU - Lisignoli, G. AU - Toneguzzi, S. AU - Piacentini, A. AU - Cristino, S. AU - Grassi, F. AU - Cavallo, C. AU - Facchini, A. PY - 2006 DA - 2006// TI - CXCL12 (SDF-1) and CXCL13 (BCA-1) chemokines significantly induce proliferation and collagen type I expression in osteoblasts from osteoarthritis patients JO - J Cell Physiol VL - 206 UR - https://doi.org/10.1002/jcp.20435 DO - 10.1002/jcp.20435 ID - Lisignoli2006 ER - TY - JOUR AU - Ishida, K. AU - Yamaguchi, M. PY - 2005 DA - 2005// TI - Albumin regulates Runx2 and alpha1 (I) collagen mRNA expression in osteoblastic cells: comparison with insulin-like growth factor-I JO - Int J Mol Med VL - 16 ID - Ishida2005 ER - TY - JOUR AU - Schreiber, B. D. AU - Hughes, M. L. AU - Groggel, G. C. PY - 1995 DA - 1995// TI - Insulin-like growth factor-1 stimulates production of mesangial cell matrix components JO - Clin Nephrol VL - 43 ID - Schreiber1995 ER - TY - JOUR AU - Fortier, L. A. AU - Nixon, A. J. AU - Lust, G. PY - 2002 DA - 2002// TI - Phenotypic expression of equine articular chondrocytes grown in three-dimensional cultures supplemented with supraphysiologic concentrations of insulin-like growth factor-1 JO - Am J Vet Res VL - 63 UR - https://doi.org/10.2460/ajvr.2002.63.301 DO - 10.2460/ajvr.2002.63.301 ID - Fortier2002 ER - TY - JOUR AU - Lam, S. AU - van der Geest, R. N. AU - Verhagen, N. A. AU - van Nieuwenhoven, F. A. AU - Blom, I. E. AU - Aten, J. AU - Goldschmeding, R. AU - Daha, M. R. AU - van Kooten, C. PY - 2003 DA - 2003// TI - Connective tissue growth factor and igf-I are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose JO - Diabetes VL - 52 UR - https://doi.org/10.2337/diabetes.52.12.2975 DO - 10.2337/diabetes.52.12.2975 ID - Lam2003 ER - TY - JOUR AU - Xin, X. AU - Hou, Y. T. AU - Li, L. AU - Schmiedlin-Ren, P. AU - Christman, G. M. AU - Cheng, H. L. AU - Bitar, K. N. AU - Zimmermann, E. M. PY - 2004 DA - 2004// TI - IGF-I increases IGFBP-5 and collagen alpha1(I) mRNAs by the MAPK pathway in rat intestinal smooth muscle cells JO - Am J Physiol Gastrointest Liver Physiol VL - 286 UR - https://doi.org/10.1152/ajpgi.00293.2003 DO - 10.1152/ajpgi.00293.2003 ID - Xin2004 ER - TY - JOUR AU - Moule, S. K. AU - Denton, R. M. PY - 1997 DA - 1997// TI - Multiple signaling pathways involved in the metabolic effects of insulin JO - Am J Cardiol VL - 80 UR - https://doi.org/10.1016/S0002-9149(97)00457-8 DO - 10.1016/S0002-9149(97)00457-8 ID - Moule1997 ER - TY - JOUR AU - Santibanez, J. F. AU - Iglesias, M. AU - Frontelo, P. AU - Martinez, J. AU - Quintanilla, M. PY - 2000 DA - 2000// TI - Involvement of the Ras/MAPK signaling pathway in the modulation of urokinase production and cellular invasiveness by transforming growth factor-beta(1) in transformed keratinocytes JO - Biochem Biophys Res Commun VL - 273 UR - https://doi.org/10.1006/bbrc.2000.2946 DO - 10.1006/bbrc.2000.2946 ID - Santibanez2000 ER - TY - JOUR AU - Sowa, H. AU - Kaji, H. AU - Yamaguchi, T. AU - Sugimoto, T. AU - Chihara, K. PY - 2002 DA - 2002// TI - Activations of ERK1/2 and JNK by transforming growth factor beta negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M206030200 DO - 10.1074/jbc.M206030200 ID - Sowa2002 ER - TY - JOUR AU - Maroun, C. R. AU - Naujokas, M. A. AU - Holgado-Madruga, M. AU - Wong, A. J. AU - Park, M. PY - 2000 DA - 2000// TI - The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase JO - Mol Cell Biol VL - 20 UR - https://doi.org/10.1128/MCB.20.22.8513-8525.2000 DO - 10.1128/MCB.20.22.8513-8525.2000 ID - Maroun2000 ER - TY - JOUR AU - Xiao, S. AU - Rose, D. W. AU - Sasaoka, T. AU - Maegawa, H. AU - Burke, T. R. AU - Roller, P. P. AU - Shoelson, S. E. AU - Olefsky, J. M. PY - 1994 DA - 1994// TI - Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction JO - J Biol Chem VL - 269 ID - Xiao1994 ER - TY - JOUR AU - Milarski, K. L. AU - Saltiel, A. R. PY - 1994 DA - 1994// TI - Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin JO - J Biol Chem VL - 269 ID - Milarski1994 ER - TY - JOUR AU - Dubois, M. J. AU - Bergeron, S. AU - Kim, H. J. AU - Dombrowski, L. AU - Perreault, M. AU - Fournes, B. AU - Faure, R. AU - Olivier, M. AU - Beauchemin, N. AU - Shulman, G. I. PY - 2006 DA - 2006// TI - The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis JO - Nat Med VL - 12 UR - https://doi.org/10.1038/nm1397 DO - 10.1038/nm1397 ID - Dubois2006 ER - TY - JOUR AU - Guévremont, M. AU - Martel-Pelletier, J. AU - Massicotte, F. AU - Tardif, G. AU - Pelletier, J. P. AU - Ranger, P. AU - Lajeunesse, D. AU - Reboul, P. PY - 2003 DA - 2003// TI - Human adult chondrocytes express hepatocyte growth factor (HGF) isoforms but not HGF: potential implication of osteoblasts for the HGF presence in cartilage JO - J Bone Miner Res VL - 18 UR - https://doi.org/10.1359/jbmr.2003.18.6.1073 DO - 10.1359/jbmr.2003.18.6.1073 ID - Guévremont2003 ER - TY - JOUR AU - Lajeunesse, D. AU - Reboul, P. PY - 2003 DA - 2003// TI - Subchondral bone in osteoarthritis: a biologic link with articular cartilage leading to abnormal remodeling JO - Curr Opin Rheumatol VL - 15 UR - https://doi.org/10.1097/00002281-200309000-00018 DO - 10.1097/00002281-200309000-00018 ID - Lajeunesse2003 ER -