Figure 3
From: Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis
Gene regions in mouse that promote (P) or inhibit (I) collagen antibody-induced arthritis (CAIA). CAIA was promoted by NOD (cia 9 quantitative trait locus (QTL)) and RIIIS/J (cia 8 and cia 1 QTL) genes, and inhibited by NOD (cia 2 QTL) and RIIIS/J (cia 5 QTL) genes. Disease modulating QTL from other arthritis mouse models are given in the background to demonstrate the co-localization of QTL. Bbaa, Borrelia burgdorferi-associated arthritis; Cia, collagen-induced arthritis; Erars, erosive arthritis susceptibility; Laq, lupus-associated arthritis QTL; Paam, progression of autoimmune arthritis in MRL mice; Pgia, proteoglycan-induced arthritis; STIA, serum transfer-induced arthritis.