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Table 1 Demographic, clinical, and therapy variables

From: Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosus

Variables All patients (n = 103) Healthy controls
Demographic variables   
   Female gender, percentage 91  
   Caucasian race, percentage 77  
   Age, years 41 ± 13  
Comorbidity   
   Diabetes mellitus, percentage 4.9  
Clinical and laboratory variables   
   Disease duration, years 6.8 ± 4  
   SLEDAI 4.7 ± 4  
   ECLAM 3.1 ± 1.6  
   SLICC/ACR damage index 1.4 ± 1.9  
   Previous biopsy proven lupus nephritis, percentage 31.1  
   Creatinine clearance <70 ml/minute, percentage 18  
   Proteinuria, percentage 13.6  
   Leucopoenia ever, percentage 36.9  
   Functional MBL serum level, median (range) μg/ml 1.4 (0.04–7.60) 1.1 (0.0–11.2)
   Functional MBL serum level <0.05 μg/ml, percentage 13 14
   MBL-induced C4 deposition on mannan, median (range) percentage 71 (1.1–399) 114 (3–494)
   MBL-induced C4 deposition on mannan <10%, percentage 21 16
   Functional activity of the MBL pathway, median (range) percentage 16 (0.1–119) 56 (0–133)
   Functional activity of the MBL pathway <10%, percentage 43 28
   C3 levels in serum, median (range) g/l 0.86 (0.06–1.70) (0.88–2.01)
   C4 levels in serum, median (range) g/l 0.13 (0.07–0.35) 0.21 (0.11–0.61)
Therapy variables   
   Oral corticosteroids   
Ever user, percentage 81  
Current user, percentage 52  
Duration of corticosteroid use in ever users, months 63 ± 70  
Actual prednisone dose if >0 mg/day, mg 13 ± 12  
   Intravenous methylprednisolone use ever, percentage 15  
   Hydroxychloroquine use ever, percentage 87  
   Azathioprine use ever, percentage 37  
   Methotrexate use ever, percentage 14  
   Cyclophosphamide (oral and/or intravenous) use ever, percentage 13  
  1. Except where indicated otherwise, values are presented as the mean ± standard deviation. ECLAM, European consensus lupus activity measurement (range 0 to 10) [35]; MBL, mannose-binding lectin; SLEDAI, systemic lupus erythematosus disease activity index (range 0 to 105) [36]; SLICC/ACR, Systemic Lupus International Collaborating Clinics/American College of Rheumatology [37].