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Table 1 Clinical characteristics of patients with rheumatoid arthritis and control subjects.

From: Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritis

Characteristic Patients with early rheumatoid arthritis (n = 89) Patients with long-standing rheumatoid arthritis (n = 66) Control subjects (n = 85) P valuea
Demographic variables     
   Age in years 51 (43–59) 57 (48–65) 52 (44–58) 0.002
   Female gender, n (percentage) 57 (64%) 49 (74%) 55 (65%) 0.35
   Caucasian, n (percentage) 81 (91%) 57 (86%) 72 (84%) 0.51
Components of the Framingham risk scoreb     
   Total cholesterol (mg/dl) 182 (156–210) 188 (149–211) 195 (171–216) 0.22
   Smoking, n (percentage) 19 (21.4%) 20 (30.3%) 8 (9.4%) 0.004
   High-density lipoprotein (mg/dl) 41 (37–53) 46 (40–56) 45 (39–54) 0.16
   Systolic blood pressure (mm Hg) 128 (116–139) 138 (124–150) 128 (115–136) 0.001
Framingham risk score (units) 11 (8–14) 14 (11–18) 12 (7–14) <0.001
Ten-year risk of a cardiovascular event 2% (1%–6%) 6% (2%–11%) 2% (1%–8%) 0.006
Other cardiovascular risk factors     
   Family history of coronary heart disease, n (percentage) 23 (26%) 19 (29%) 26 (31%) 0.78
   Body mass index (kg/m2) 28 (25–34) 28 (24–31) 27 (25–32) 0.51
   Low-density lipoprotein (mg/dl) 111 (93–135) 114 (83–135) 122 (104–145) 0.07
   Lp(a) lipoprotein (mg/dl) 8.1 (2.0–24.6) 8.7 (4.0–23.2) 9.9 (4.0–32.3) 0.24
   Triglycerides (mg/dl) 108 (78–141) 111 (81–172) 103 (74–135) 0.43
   Homocysteine (μmol/l) 9.5 (8.1–11.4) 10.7 (8.1–12.3) 8.2 (7.1–9.6) <0.001
  1. aP values were calculated using Fisher's exact test for categorical variables and Wilcoxon rank sum test for continuous variables;
  2. bOther than age and gender. Continuous values are presented as median (interquartile range).