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Figure 6 | Arthritis Research & Therapy

Figure 6

From: Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients

Figure 6

Association between the relative ratios of insulin-like growth factor (IGF)-II/GAPDH mRNA and IGF-I/GAPDH mRNA. Gene expression was determined in intertrochanteric trabecular bone from patients with osteoarthritis (OA) (n = 15) and controls (n = 13). A significant correlation was observed between the two parameters in patients with OA (IGF-II/GAPDH = 1.49 [IGF-I/GAPDH] + 0.01; r = 0.64, p < 0.02) and controls (IGF-II/GAPDH = 1.34 [IGF-I/GAPDH] – 0.09; r = 0.73, p < 0.005). GAPDH, glyceraldehyde-3-phosphate dehydrogenase.

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