Figure 4From: Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explantsThe VEGF content of medium supernatant (as determined by ELISA). Stimulation of immortalized chondrocytes (a) and articular cartilage explants (b) with PMA (μg per 1 ml of medium) or SIN-1 (μM). The level of VEGF protein is increased after stimulation with PMA or SIN-1. Results are shown as mean ± standard error of the mean for five separate experiments. * p < 0.05 versus Con. Con, control; PMA, phorbol myristate acetate; SIN-1, 3-morpholino-sydnonimine hydrochloride; VEGF, vascular endothelial growth factor.Back to article page