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Table 1 Microscopic variables for fibroblast-like synovial cells

From: Effects of hyaluronan treatment on lipopolysaccharide-challenged fibroblast-like synovial cells

  Day 1 (pre-lipopolysaccharide challenge) Day 1 (post-lipopolysaccharide challenge) Day 2
  Group 1 Group 2 Group 3 Group 4 Group 1 Group 2 Group 3 Group 4 Group 1 Group 2 Group 3 Group 4
Cellular morphology (median and range) 0 (0-0) 0 (0-0) 0 (0-0) 0 (0-0) 0 (0-0) 3a (0–4) 4a (3–4) 1 (0–4) 0 (0-0) 3b (0–4) 4b (3–4) 0 (0–4)
Cell count (104) (mean ± SEM) 20 20 20 20 - - - - 118c ± 33 46 ± 3 32 ± 1 49 ± 7
Cell viability (%) (mean ± SEM) - - - - - - - - 97 ± 0.3 96 ± 1.2 94 ± 2.6 96 ± 0.1
  1. Triplicate samples were performed for each of the three individual donors in the four groups. Group 1, unchallenged control; group 2, lipopolysaccharide control; group 3, pretreatment and sustained treatment with lower molecular weight hyaluronan product; group 4, pretreatment and sustained treatment with higher molecular weight hyaluronan product. 0, >95% attached; 1, 5–25% detached; 2, 26–50% detached; 3, 51–75% detached; 4, >76% detached. SEM, standard error of the mean; -, values not determined. a,b,cSignificant difference exists (P < 0.05).