Figure 1 From: Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis The synthesis of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-dexamethasone conjugate. Conjugation to dexamethasone may occur at either the 3 or the 20 carbonyl group (an example of the latter is shown). AIBN, 2,2'-azobisisobutyronitrile; Boc-NHNH2, carbazic acid tert-butyl ester; DCC, N, N'-dicyclohexylcarbodiimide; TFA, trifluroacetic acid.Back to article page