Figure 3

Bone mineral density (BMD) measurement of healthy and adjuvant-induced arthritis (AIA) rats. BMD was evaluated with peripheral dual x-ray absorptiometry at the ankle, femur, and the fourth and fifth lumbar vertebral bodies. *Significantly different from the healthy control group, p < 0.05. **Significantly different from the AIA+saline group, p < 0.05. ***Significantly different from the AIA+Dex group, p < 0.05. Dex, dexamethasone; P-Dex, N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-dexamethasone conjugate.