Figure 8

NS398 increases foam cell formation in THP-1 macrophages. THP-1 differentiated macrophages were treated with acetylated low-density lipoprotein (50 μg/ml, 48 hours) and further incubated alone or with the addition of NS398 (10 μM, 18 hours). Representative photomicrographs of oil red O staining to detect foam cells. NS398, N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide.