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Table 1 Concentration of IL-6 and PGE2 in supernatants from cultured FLS cells and co-cultures from FLS cells and DRG neurones

From: Fibroblast-like synovial cells from normal and inflamed knee joints differently affect the expression of pain-related receptors in sensory neurones: a co-culture study

  PGE2 (ng/ml) IL-6 (ng/ml)
DRG neurones ND ND
FLS cells, normal knee joints 4.8 ± 2.1 10.6 ± 2.2
FLS cells, acutely inflamed knee joints 28.6 ± 5.2 22.0 ± 4.2
FLS cells, chronically inflamed knee joints 92.9 ± 23.4 NM
DRG neurones + FLS cells, normal knee joints 11.7 ± 3.1 12.8 ± 2.0
DRG neurones + FLS cells, acutely inflamed joints 39.0 ± 4.1 26.0 ± 3.9
DRG neurones + FLS cells, chronically inflamed joints 75.7 ± 18.5 NM
  1. DRG, dorsal root ganglion; FLS, fibroblast-like synovial; IL, interleukin; ND, not detected; NM, not measured; PGE2, prostaglandin E2.