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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain

Figure 5

Effect of lacosamide and morphine on mechanical hyperalgesia after monosodium iodoacetate (MIA) injection. Effect of lacosamide and morphine on paw withdrawal threshold in the paw pressure test in MIA-treated animals on (a) day 3, (b) day 7 and (c) day 14 after arthritis induction. Rats were tested 45 to 60 minutes post-drug. Data from 12 animals/group are presented as mean ± SEM. *P < 0.05 Dunnett's test versus MIA/vehicle treated animals.

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