Figure 5 From: Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain Effect of lacosamide and morphine on mechanical hyperalgesia after monosodium iodoacetate (MIA) injection. Effect of lacosamide and morphine on paw withdrawal threshold in the paw pressure test in MIA-treated animals on (a) day 3, (b) day 7 and (c) day 14 after arthritis induction. Rats were tested 45 to 60 minutes post-drug. Data from 12 animals/group are presented as mean ± SEM. *P < 0.05 Dunnett's test versus MIA/vehicle treated animals.Back to article page