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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Therapy for pneumonitis and sialadenitis by accumulation of CCR2-expressing CD4+CD25+regulatory T cells in MRL/lpr mice

Figure 4

Evaluation of pneumonitis and sialadenitis in Treg cell- and CCR2-Treg cell-transferred MRL/lpr mice. The degrees of pneumonitis and sialadenitis of control and treated 17-week-old MRL/lpr mice were scored as described in Materials and methods. Values are presented as the mean and standard deviation (n = 5 to 7 mice per group). Similar results were observed in two independent experiments. *P < 0.01 versus control by Student's t test. CCR2-Treg cell, CD4+CD25+Foxp3+ CCR2-transfected T cell; MRL/lpr, MRL/MpJ-lpr/lpr; Treg cell, CD4+CD25+Foxp3+ T cell.

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