Mouse knee swelling measurement. Galectin-3 (gal-3) was injected in both knees. Animals were examined daily and knee diameter measured using a digital calliper as described in Materials and methods. The swelling corresponded to the difference between joint diameter measured every day and joint diameter prior to the injection (D0). D0 was given the value of 0. Control (Ctl): injection of PBS. Each group contained four animals. *p versus same conditions as D0; #p versus control of the corresponding day.