|
Age (years)
|
45.0 (6.6)
|
47.2 (5.4)
|
0.148
|
|
Sex (female [%])
|
59
|
43
|
0.150*
|
|
Family history of OA (positive [%])
|
45
|
57
|
0.284*
|
|
Height (cm)
|
169.0 (8.5)
|
172.1 (8.2)
|
0.102
|
|
Weight (kg)
|
76.6 (14.6)
|
92.7 (21.5)
|
< 0.001
|
|
BMI (kg/m2)
|
26.8 (4.5)
|
31.3 (7.0)
|
< 0.001
|
|
Knee pain (%)
|
33
|
38
|
0.665*
|
|
Obese (%)
|
18
|
52
|
< 0.001*
|
|
Past knee injury (%)
|
19
|
38
|
0.037*
|
|
Medial tibial cartilage volume (ml)
|
2.2 (0.5)
|
2.4 (0.5)
|
0.051
|
|
Lateral tibial cartilage volume (ml)
|
2.6 (0.7)
|
2.7 (0.6)
|
0.408
|
|
Medial femoral cartilage volume (ml)
|
4.6 (1.3)
|
4.7 (1.0)
|
0.632
|
|
Lateral femoral cartilage volume (ml)
|
4.7 (1.3)
|
5.1 (1.0)
|
0.280
|
|
Medial tibial bone area (cm2)
|
17.3 (2.6)
|
19.8 (3.8)
|
< 0.001
|
|
Lateral tibial bone area (cm2)
|
11.9 (2.0)
|
13.5 (2.5)
|
0.001
|
|
Medial tibiofemoral cartilage defect (0–8)
|
2.0 (0.6)
|
3.1 (1.4)
|
< 0.001
|
|
Lateral tibiofemoral cartilage defect (0–8)
|
2.0 (0.7)
|
2.1 (0.7)
|
0.550
|
|
Any radiographic osteoarthritis (%)
|
15
|
52
|
< 0.001*
|
|
Medial joint space narrowing (%)
|
13
|
38
|
0.001*
|
|
Medial osteophytes (%)
|
4
|
43
|
< 0.001*
|
|
Lateral joint space narrowing (%)
|
3
|
5
|
0.737*
|
|
Lateral osteophytes (%)
|
3
|
14
|
< 0.001*
|
|
Change in medial tibial cartilage volume (%)
|
-2.4 (4.1)
|
-4.7 (4.4)
|
0.015
|
|
Change in lateral tibial cartilage volume (%)
|
-1.5 (3.4)
|
-1.6 (3.8)
|
0.860
|
|
Change in medial femoral cartilage volume (%)
|
-3.3 (2.6)
|
-4.1 (3.9)
|
0.278
|
|
Change in lateral femoral cartilage volume (%)
|
-3.3 (2.5)
|
-3.5 (3.1)
|
0.662
|
|
Change in medial tibial bone area (%)
|
+0.7 (1.8)
|
+0.2 (1.7)
|
0.258
|
|
Change in lateral tibial bone area (%)
|
+0.3 (2.8)
|
+0.5 (2.4)
|
0.781
|
|
Change in medial tibiofemoral cartilage defect
|
-0.07 (0.86)
|
0.29 (1.06)
|
0.074
|
|
Change in lateral tibiofemoral cartilage defect
|
-0.02 (0.81)
|
0.50 (1.20)
|
0.007
|
