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Table 1 Characteristics of subjects with and without baseline medial meniscal extrusion
| Characteristic | Meniscal extrusion at baseline | P value | |
|---|---|---|---|
| Negative (n = 273) | Positive (n = 21) | ||
| Age (years) | 45.0 (6.6) | 47.2 (5.4) | 0.148 |
| Sex (female [%]) | 59 | 43 | 0.150* |
| Family history of OA (positive [%]) | 45 | 57 | 0.284* |
| Height (cm) | 169.0 (8.5) | 172.1 (8.2) | 0.102 |
| Weight (kg) | 76.6 (14.6) | 92.7 (21.5) | < 0.001 |
| BMI (kg/m2) | 26.8 (4.5) | 31.3 (7.0) | < 0.001 |
| Knee pain (%) | 33 | 38 | 0.665* |
| Obese (%) | 18 | 52 | < 0.001* |
| Past knee injury (%) | 19 | 38 | 0.037* |
| Medial tibial cartilage volume (ml) | 2.2 (0.5) | 2.4 (0.5) | 0.051 |
| Lateral tibial cartilage volume (ml) | 2.6 (0.7) | 2.7 (0.6) | 0.408 |
| Medial femoral cartilage volume (ml) | 4.6 (1.3) | 4.7 (1.0) | 0.632 |
| Lateral femoral cartilage volume (ml) | 4.7 (1.3) | 5.1 (1.0) | 0.280 |
| Medial tibial bone area (cm2) | 17.3 (2.6) | 19.8 (3.8) | < 0.001 |
| Lateral tibial bone area (cm2) | 11.9 (2.0) | 13.5 (2.5) | 0.001 |
| Medial tibiofemoral cartilage defect (0–8) | 2.0 (0.6) | 3.1 (1.4) | < 0.001 |
| Lateral tibiofemoral cartilage defect (0–8) | 2.0 (0.7) | 2.1 (0.7) | 0.550 |
| Any radiographic osteoarthritis (%) | 15 | 52 | < 0.001* |
| Medial joint space narrowing (%) | 13 | 38 | 0.001* |
| Medial osteophytes (%) | 4 | 43 | < 0.001* |
| Lateral joint space narrowing (%) | 3 | 5 | 0.737* |
| Lateral osteophytes (%) | 3 | 14 | < 0.001* |
| Change in medial tibial cartilage volume (%) | -2.4 (4.1) | -4.7 (4.4) | 0.015 |
| Change in lateral tibial cartilage volume (%) | -1.5 (3.4) | -1.6 (3.8) | 0.860 |
| Change in medial femoral cartilage volume (%) | -3.3 (2.6) | -4.1 (3.9) | 0.278 |
| Change in lateral femoral cartilage volume (%) | -3.3 (2.5) | -3.5 (3.1) | 0.662 |
| Change in medial tibial bone area (%) | +0.7 (1.8) | +0.2 (1.7) | 0.258 |
| Change in lateral tibial bone area (%) | +0.3 (2.8) | +0.5 (2.4) | 0.781 |
| Change in medial tibiofemoral cartilage defect | -0.07 (0.86) | 0.29 (1.06) | 0.074 |
| Change in lateral tibiofemoral cartilage defect | -0.02 (0.81) | 0.50 (1.20) | 0.007 |
