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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes

Figure 2

Regulation of CD36 mRNA expression by tumor necrosis factor (TNF)α and adalimumab. TNFα decreases CD36 mRNA expression and adalimumab increases CD36 mRNA expression. Human monocytes were incubated with macrophage-serum-free medium (M-SFM) alone (control), or with M-SFM containing TNFα (10 ng/ml) or adalimumab (Ada; 1 μg/ml) for 4 h. CD36 mRNA expression was quantified using RT-PCR and normalized to β-actin. Data represent the mean ± standard error of the relative quantification of CD36 mRNA expression measured in three experiments. *Significantly different from control (p < 0.05).

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