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Table 1 In vivo evidence supporting a role for BMPs in cartilage homeostasis

From: Bone morphogenetic proteins in destructive and remodeling arthritis

Pro-homeostatic effects Normal BMP receptor type Ia [35]
  Noggin haploinsufficiency [18]
  Injection of BMP2 [22]
Anti-homeostatic effects Noggin overexpression [18]
  1. BMP, bone morphogenetic protein.