Skip to main content

Table 2 Controlled studies of stress testing using the tilt table or heart rate variability analysis in patients with fibromyalgia

From: Biology and therapy of fibromyalgia. Stress, the stress response system, and fibromyalgia

Reference Type of stress test Number of patients Number of controls Main conclusion
Martinez-Lavin and colleagues, 1997 [18] Active orthostatic stress 19 19 Orthostatic sympathetic derangement
Bou-Holaigah and colleagues, 1997 [19] Head-up tilt table test 20 (17 female) 20 (18 female) Hypotension in 60% of patients (0% in controls)
Raj and colleagues, 2000 [13] Head-up tilt table test 17 14 Positive test in 64% of patients and 21 controls
Naschitz and colleagues, 2001 [20] 'Discriminant score' during head-up tilt table test 38 (67% female) 30 with chronic fatigue syndrome (58% female), 37 normal (65% female) Discriminant score different in fibromyalgia versus chronic fatigue syndrome
Friederich and colleagues, 2005 [21] Mental stress, passive orthostatism 28 15 Less sympathetic activation
Furlan and colleagues, 2005 [16] Head-up tilt table test, muscular sympathetic nerve activity 16 (15 female) 16 (15 female) Decreased sympathetic response