Figure 5
From: Microenvironmental changes during differentiation of mesenchymal stem cells towards chondrocytes
Expression levels of ADAM and adhesion molecules during chondrogenic differentiation of mesenchymal stem cells (MSCs). The gene-expression profile of mesenchymal stem cells (MSCs; n = 2) was analysed by real-time PCR during their differentiation towards chondrocytes in micropellets. Change in the expression levels of various ADAM family members (a), several cadherins and CAMs (b) and a number of integrins (c). ADAM, A Disintegrin And Metalloproteinase molecule; ALCAM, activated leukocyte CAM; CAM, cell-adhesion molecule; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; ICAM, intercellular CAM; MCAM, melanoma CAM; NRCAM, neuronal CAM; PCR, polymerase chain reaction; ADAMTS, A Disintegrin And Metalloproteinase with thrombospondin type 1 motif; VCAM, vascular cell adhesion molecule.