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Table 4 Geometric means (percentage of the coefficient of variation) of antibody titers taken 14 and 28 days after pneumococcal vaccination

From: Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects

Group

n

Baseline (μg/ml)

14 days post-vaccination (μg/ml)

28 days post-vaccination (μg/ml)

Serotype 14

    

   Group A

20

1.9 (112)

20.5 (236)

23.5 (199)

   Group B

20

1.9 (132)

15.5 (105)

15.4 (111)a

   Group C

19

1.8 (201)

12.0 (195)

12.8 (250)

   Group D

19

1.8 (125)

18.0 (155)

12.6 (141)

Serotype 2

    

   Group A

20

1.0 (163)

13.4 (113)

15.4 (110)

   Group B

20

1.1 (84)

12.3 (109)

13.2 (107)a

   Group C

19

0.8 (90)

4.1 (118)

4.8 (115)

   Group D

19

0.7 (122)

7.0 (132)

7.7 (136)

Serotype 23F

    

   Group A

20

0.9 (101)

3.0 (112)

3.3 (113)

   Group B

20

1.8 (124)

5.6 (87)

4.9 (89)a

   Group C

19

1.2 (158)

4.5 (112)

5.1 (106)

   Group D

19

1.5 (125)

6.2 (92)

6.7 (90)

Serotype 8

    

   Group A

20

1.5 (120)

10.1 (138)

9.6 (114)

   Group B

20

2.3 (104)

12.0 (61)

10.5 (81)a

   Group C

19

1.4 (104)

4.0 (68)

4.4 (64)

   Group D

19

1.6 (74)

5.1 (144)

5.2 (106)

Serotype 9V

    

   Group A

20

0.9 (148)

6.1 (102)

6.4 (99)

   Group B

20

1.3 (158)

4.0 (97)

3.9 (101)a

   Group C

19

0.9 (190)

3.0 (147)

3.2 (108)

   Group D

19

0.9 (119)

2.0 (107)

2.3 (106)

Serotype 19F

    

   Group A

20

5.3 (95)

13.0 (125)

13.9 (150)

   Group B

20

10.3 (127)

19.9 (105)

19.6 (97)a

   Group C

19

4.3 (117)

10.0 (178)

10.3 (180)

   Group D

19

5.6 (75)

9.9 (89)

10.3 (88)

Serotype 6B

    

   Group A

20

1.6 (103)

5.9 (197)

6.1 (204)

   Group B

20

3.1 (126)

7.8 (87)

7.1 (95)a

   Group C

19

1.9 (140)

4.6 (147)

4.6 (141)

   Group D

19

1.8 (114)

3.5 (159)

3.5 (151)

  1. an = 19.