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Table 1 Selected genes induced by keratinocyte-fibroblast interactions

From: Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions

Type of gene

Details

Extracellular matrix (ECM)

Collagens

 

Hyaluronan synthase 2

 

Lysylhydroxylase 2

 

Transglutaminase 2

 

Tenascin C

 

Decorin

 

Syndecan 2

Cell-cell signalling

Monocyte chemoattractant protein (MCP)-1

 

Activin A

 

Latent TGF-β-binding protein (LTBP)1

 

Interleukin (IL)-6

 

Connective tissue growth factor (CTGF)

 

Heparin-binding epithelial growth factor (HB-EGF)

 

Endothelin (ET)-1

 

Angiopoietin 1

 

Cyclo-oxygenase (COX)-2

 

Granulocyte-colony stimulating factor (G-CSF)

Cytoskeleton

α-Smooth muscle actin (α-SMA)

 

Integrins

 

Tropomyosin

 

Vasodilator-stimulated phosphoprotein (VASP)

 

Myosin light chain kinase (MLCK)

  1. Taken from [30].