Skip to main content

Table 3 PTPN22 R620W polymorphism and links with immune diseases

From: Genetic factors in systemic sclerosis

Association identified

No association

Scleroderma: ATA positive and ACA positive

Multiple sclerosis

RA and JRA

Coeliac disease

SLE

Primary sclerosis cholangitis

Type I diabetes mellitus

Crohn's disease

Grave's and Addison's

Psoriasis

Psoriatic arthritis

Ankylosing spondylitis

Wegener's granulomatosis

Primary Sjögren's syndrome

  1. This area of research is reviewed by Gregersen and Batliwalla [18]. ACA, anticentromere antibody; ATA, antitopoisomerase antibody; JRA, juvenile rheumatoid arthritis; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus.