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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice

Figure 2

Hind paw images of DBA mice. (a) Hind paws of healthy non-immunized DBA mice. (b) Type II collagen-immunized (arthritic) DBA mice treated with 1-methyl-tryptophan 6 to 7 days after the onset of collagen-induced arthritis. (c) Type II collagen-immunized (arthritic) DBA mice treated with vehicle 6 to 7 days after the onset of collagen-induced arthritis. According to our scoring system (see Materials and methods), the three stages have been assigned scores of 0 (a), 4 (b), and 3 (c).

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