From: Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: a nested case-control study
Predictor
Adjusted OR
95% CI
p
Proton-pump inhibitors
0.33
0.17–0.67
0.002
Coumarin
2.09
0.93–4.70
0.075
Heart failure
2.44
1.28–4.66
0.007
Acetaminophen
2.80
1.64–4.79
<0.001
Low-molecular-mass heparin
17.33
3.71–80.95