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Table 1 mRNA transcript expression in microarray

From: Expression of inflammatory host genes in Chlamydia trachomatis-infected human monocytes

Time course

Cytokines

Accession number

4 hours pi

1 day pi

7 days pi

3 time points

IFN-γ

X01992

+++

++

+

2 time points

IL-5

X04688

+++

+

-

 

IL-1-β

K02770

-

+

+

 

IL-10

M57627

-

+

+

 

TGF-β-2

M19154

-

+

+

1 time point

TNF-α

X01394

+++

-

-

 

LIF

X13967

+++

-

-

 

IL-4

M13982

+++

-

-

 

IL-6

X04602

+++

-

-

 

IL-15

U14407

+

-

-

 

IL-16

M90391

+

-

-

 

IL-17 (CTLA8)

U32659

+++

-

-

 

IL-18

D49950

+++

-

-

 

IL-1-α

X02851

-

+

-

 

IL-3

M14743

-

+

-

 

IL-9

X17543

-

+

-

 

IL-11

M57765

-

+

-

 

TGF-β-1

X02812

-

-

+

  1. The table shows mRNA transcripts encoding for cytokines as found to be expressed by microarray in Chlamydia trachomatis-infected human monocytes over a time course of up to 7 days. Signal intensity is given as fold of expression as compared with the mock-infected probe. Fold of expression for microarray as well as for reverse transcription-polymerase chain reaction data is indicated by '-' (less than 2), '+' (more than or equal to 2 and less than 10), '++' (more than or equal to 10 and less than 100), and '+++' (more than or equal to 100). Gene expression was studied at three different time points: 4 hours pi indicates the very early phase of active infection, whereas day 1 corresponds to a transition (that is, the beginning of growth arrest) and day 7 represents persistent infection. IFN, interferon; IL, interleukin; LIF, leukemia inhibitory factor; pi, post-infection; TGF, transforming growth factor; TNF, tumor necrosis factor.