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Table 3 mRNA transcript expression in microarray

From: Expression of inflammatory host genes in Chlamydia trachomatis-infected human monocytes

Time course Receptors Accession number 4 hours pi 1 day pi 7 days pi
3 time points IL-2R-γ D11086 + (+) + (-) + (+)
1 time point IL-2R-β (CD122) M26062 + - -
  IL-5R-α (CD125) M75914 - + -
  TNFR M32315 - - +
  1. The table shows mRNA transcripts encoding for cytokine and chemokine receptors as found to be expressed by microarray in Chlamydia trachomatis-infected human monocytes over a time course of up to 7 days. Microarray ratios of interleukin-2 receptor-gamma (IL-2R-γ) were confirmed by quantitative real-time reverse transcription-polymerase chain reaction (noted in parentheses) (see Figures 1–3). Fold of expression for microarray as well as for reverse transcription-polymerase chain reaction data is indicated by '-' (less than 2), '+' (more than or equal to 2 and less than 10), '++' (more than or equal to 10 and less than 100), and '+++' (more than or equal to 100). Gene expression was studied at three different time points: 4 hours pi indicates the very early phase of active infection, whereas day 1 corresponds to a transition (that is, the beginning of growth arrest) and day 7 represents persistent infection. IL-5R-α, interleukin-5 receptor-alpha; TNFR, tumor necrosis factor receptor.