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Table 2 Frequency distribution of the 1858 C/T polymorphism of PTPN22 in patients with early rheumatoid arthritis and matched controls

From: The PTPN221858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden

Genotype Patients (n = 504) Controls (n = 970) χ2 P value Pc value Odds ratio 95% confidence interval
  n % n %      
CC 338 67.1 761 78.5 22.68 0.000002 0.00001 0.56 0.44–0.72
CT 151 30.0 196 20.2 17.53 0.000028 0.00014 1.69 1.31–2.18
TT 15 3.0 13 1.3 4.76 0.02907 0.14535 2.26 1.01–5.08
CT + TT 166 33.0 209 21.5 22.68 0.000002 0.00001 1.79 1.40–2.29
T allele 181 18.0 222 11.4 23.84 0.000001 0.000005 1.69 1.36–2.11
  1. Pc, corrected P value.