| |
Non-T carrier (CC)
|
T carrier (CT, TT)
|
|---|
| |
Cases/controls
|
Relative risk (95% confidence interval)
|
Cases/controls
|
Relative risk (95% confidence interval)
|
|---|
|
Anti-CCP antibody-positive
|
|
Smoking-negative
|
59/511
|
1.00
|
37/146
|
2.17 (1.41–3.35)
|
|
Smoking-positive
|
142/192
|
6.29 (4.51–8.77)
|
73/50
|
12.54 (8.11–19.40)
|
|
Anti-CCP antibody-negative
|
|
Smoking-negative
|
47/511
|
1.00
|
17/146
|
1.36 (0.80–2.33)
|
|
Smoking-positive
|
60/192
|
3.71 (2.51–5.46)
|
23/50
|
5.87 (3.46–9.95)
|
- The combination of carriage or not of the 1858T variant of the PTPN22 gene and ever or never smoking were compared for groups stratified for anti-CCP antibodies.
