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Table 2 DQA1 allele distribution in rheumatic heart disease patients compared with control subjects

From: HLA class II DR and DQ genotypes and haplotypes associated with rheumatic fever among a clinically homogeneous patient population of Latvian children

  Allele
Group DQA1*0102 DQA1*0201 DQA1*0401 DQA1*0501 DQA1*0301
All RF (n = 140) 0.13/0.34 (0.001) 0.12 0.11/3.31 (0.01) 0.29 0.16
MVR (n = 48) 0.08 0.08 0.08 0.29 0.23
MVL (n = 40) 0.23 0.10 0.07/4.87 (0.05) 0.37/3.25 (0.03) 0.17/3.45 (0.02)
Chorea minor (n = 16) 0.13 0.31/3.33 (0.05) 0.00 0.19 0.31/2.91 (0.05)
Without RHD (n = 46) 0.13 0.17 0.06 0.24 0.13
Control subjects (n = 200) 0.21 0.12 0.03 0.24 0.13
  1. Values are allele frequency/odds ratio (p value) and are reported only for significant associations (p < 0.05); n = number of haplotypes (for example, 140 alleles from 70 individuals and 200 alleles from 100 individuals). MVL, multivavular lesion (mitral regurgitation + aortic valve regurgitation; MVR, mitral valve regurgitation; RF, rheumatic fever; RHD, rheumatic heart disease.