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Table 2 DQA1 allele distribution in rheumatic heart disease patients compared with control subjects

From: HLA class II DR and DQ genotypes and haplotypes associated with rheumatic fever among a clinically homogeneous patient population of Latvian children

 

Allele

Group

DQA1*0102

DQA1*0201

DQA1*0401

DQA1*0501

DQA1*0301

All RF (n = 140)

0.13/0.34 (0.001)

0.12

0.11/3.31 (0.01)

0.29

0.16

MVR (n = 48)

0.08

0.08

0.08

0.29

0.23

MVL (n = 40)

0.23

0.10

0.07/4.87 (0.05)

0.37/3.25 (0.03)

0.17/3.45 (0.02)

Chorea minor (n = 16)

0.13

0.31/3.33 (0.05)

0.00

0.19

0.31/2.91 (0.05)

Without RHD (n = 46)

0.13

0.17

0.06

0.24

0.13

Control subjects (n = 200)

0.21

0.12

0.03

0.24

0.13

  1. Values are allele frequency/odds ratio (p value) and are reported only for significant associations (p < 0.05); n = number of haplotypes (for example, 140 alleles from 70 individuals and 200 alleles from 100 individuals). MVL, multivavular lesion (mitral regurgitation + aortic valve regurgitation; MVR, mitral valve regurgitation; RF, rheumatic fever; RHD, rheumatic heart disease.
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Arthritis Research & Therapy

ISSN: 1478-6362

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