| |
Allele
|
|---|
|
Group
|
DQA1*0102
|
DQA1*0201
|
DQA1*0401
|
DQA1*0501
|
DQA1*0301
|
|---|
|
All RF (n = 140)
|
0.13/0.34 (0.001)
|
0.12
|
0.11/3.31 (0.01)
|
0.29
|
0.16
|
|
MVR (n = 48)
|
0.08
|
0.08
|
0.08
|
0.29
|
0.23
|
|
MVL (n = 40)
|
0.23
|
0.10
|
0.07/4.87 (0.05)
|
0.37/3.25 (0.03)
|
0.17/3.45 (0.02)
|
|
Chorea minor (n = 16)
|
0.13
|
0.31/3.33 (0.05)
|
0.00
|
0.19
|
0.31/2.91 (0.05)
|
|
Without RHD (n = 46)
|
0.13
|
0.17
|
0.06
|
0.24
|
0.13
|
|
Control subjects (n = 200)
|
0.21
|
0.12
|
0.03
|
0.24
|
0.13
|
- Values are allele frequency/odds ratio (p value) and are reported only for significant associations (p < 0.05); n = number of haplotypes (for example, 140 alleles from 70 individuals and 200 alleles from 100 individuals). MVL, multivavular lesion (mitral regurgitation + aortic valve regurgitation; MVR, mitral valve regurgitation; RF, rheumatic fever; RHD, rheumatic heart disease.
