| |
Genotype
|
|---|
|
Group
|
*07/*0201
|
*01/*0501
|
*04/*0401
|
|---|
|
All RF (n = 70)
|
0.09/2.01 (0.06)
|
0.08/3.18 (0.005)
|
0.01/0.23
|
|
MVR (n = 24)
|
0.06
|
0.06
|
ND
|
|
MVL (n = 20)
|
0.1
|
0.01/5.69 (0.001)
|
ND
|
|
Sydenham's chorea (n = 8)
|
0.18/3.72 (0.04)
|
0.05
|
ND
|
|
Without RHD (n = 23)
|
0.13/2.79 (0.02)
|
0.06
|
0.001/11.10 (0.004)
|
|
Control subjects (n = 100)
|
0.05
|
1.44/0.23
|
0.19/0.65
|
- Values are allele frequency/odds ratio (p value) and are reported only for significant associations (p < 0.05); n = number of haplotypes (for example, 140 alleles from 70 individuals and 200 alleles from 100 individuals). MVL, multivalvular lesion (mitral regurgitation + aortic valve regurgitation; MVR, mitral valve regurgitation; ND, not determined; RF, rheumatic fever; RHD, rheumatic heart disease.
