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Table 4 DRB1/DQA1 genotype distribution in rheumatic fever and rheumatic heart disease patients compared with control subjects

From: HLA class II DR and DQ genotypes and haplotypes associated with rheumatic fever among a clinically homogeneous patient population of Latvian children

  Genotype
Group *07/*0201 *01/*0501 *04/*0401
All RF (n = 70) 0.09/2.01 (0.06) 0.08/3.18 (0.005) 0.01/0.23
MVR (n = 24) 0.06 0.06 ND
MVL (n = 20) 0.1 0.01/5.69 (0.001) ND
Sydenham's chorea (n = 8) 0.18/3.72 (0.04) 0.05 ND
Without RHD (n = 23) 0.13/2.79 (0.02) 0.06 0.001/11.10 (0.004)
Control subjects (n = 100) 0.05 1.44/0.23 0.19/0.65
  1. Values are allele frequency/odds ratio (p value) and are reported only for significant associations (p < 0.05); n = number of haplotypes (for example, 140 alleles from 70 individuals and 200 alleles from 100 individuals). MVL, multivalvular lesion (mitral regurgitation + aortic valve regurgitation; MVR, mitral valve regurgitation; ND, not determined; RF, rheumatic fever; RHD, rheumatic heart disease.