| |
Genotype
|
|---|
|
Group
|
*0102/*0602-8
|
*0501/*0301
|
*0501/*0201-2
|
*0301/*0402
|
|---|
|
All RF (n = 70)
|
0.09
|
0.19/2.10 (0.01)
|
0.01/0.26 (0.05)
|
0.03/7.06 (0.03)
|
|
MVR (n = 24)
|
0.06
|
0.15
|
0.02
|
ND
|
|
MVL (n = 20)
|
0.12
|
0.25/3.35 (0.01)
|
ND
|
0.02
|
|
Sydenham's chorea (n = 8)
|
0.12
|
0.12
|
ND
|
0.12/38.83 (0.005)
|
|
Without RHD (n = 23)
|
0.12
|
0.22/2.58 (0.03)
|
0.02
|
0.07/17.48 (0.0005)
|
|
Control subjects (n = 100)
|
0.12/198.63 (0.00)
|
0.11
|
0.05
|
0.004
|
- Values are allele frequency/odds ratio (p value) and are reported only for significant associations (p < 0.05); n = number of haplotypes (for example, 140 alleles from 70 individuals and 200 alleles from 100 individuals). MVL, multivavular lesion (mitral regurgitation + aortic valve regurgitation); MVR, mitral valve regurgitation; ND, not determined; RF, rheumatic fever; RHD, rheumatic heart disease.
