Table 3 Top 30 differentially regulated pathways in rheumatoid arthritis using Gene Set Enrichment Analysis
Rank | Name | Sizea | NES |
|---|---|---|---|
1 | Inflammatory_Response_Pathway | 42 | -1.7343 |
2 | CR_IMMUNE_FUNCTION | 72 | -1.4860 |
3 | cell_motility | 148 | -1.3477 |
4 | il7Pathway | 37 | -1.3376 |
5 | breast_cancer_estrogen_signalling | 167 | -1.2575 |
6 | TGF_Beta_Signaling_Pathway | 76 | -1.2538 |
7 | p38mapkPathway | 72 | -1.2517 |
8 | TGF_joint | 91 | -1.2494 |
9 | ST_Ga12_Pathway | 36 | -1.2444 |
10 | P53_UP | 55 | -1.2301 |
11 | SA_CASPASE_CASCADE | 31 | -1.2147 |
12 | Wnt_Signaling | 79 | -1.2121 |
13 | fasPathway | 60 | -1.1990 |
14 | EMT_DOWN | 56 | -1.1655 |
15 | CR_CAM | 143 | -1.1651 |
16 | cell_adhesion | 245 | -1.1628 |
17 | NFKB_REDUCED | 30 | -1.1577 |
18 | mRNA_processing | 55 | -1.1485 |
19 | ST_MONOCYTE_AD_PATHWAY | 39 | -1.1485 |
20 | GPCRs_Class_B_Secretin-like | 28 | -1.1401 |
21 | GLUCOSE_DOWN | 261 | -1.1364 |
22 | tnf_and_fas_network | 33 | -1.1302 |
23 | ST_Fas_Signaling_Pathway | 97 | -1.1263 |
24 | shh_lisa | 33 | -1.1164 |
25 | intrinsicPathway | 28 | -1.1160 |
26 | tgfbPathway | 35 | -1.0937 |
27 | alkPathway | 57 | -1.0871 |
28 | hdacPathway | 45 | -1.0860 |
29 | 41bbPathway | 33 | -1.0787 |
30 | ST_Ga13_Pathway | 54 | -1.0367 |