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Table 3 Top 30 differentially regulated pathways in rheumatoid arthritis using Gene Set Enrichment Analysis

From: Constitutive upregulation of the transforming growth factor-β pathway in rheumatoid arthritis synovial fibroblasts

Rank Name Sizea NES
1 Inflammatory_Response_Pathway 42 -1.7343
2 CR_IMMUNE_FUNCTION 72 -1.4860
3 cell_motility 148 -1.3477
4 il7Pathway 37 -1.3376
5 breast_cancer_estrogen_signalling 167 -1.2575
6 TGF_Beta_Signaling_Pathway 76 -1.2538
7 p38mapkPathway 72 -1.2517
8 TGF_joint 91 -1.2494
9 ST_Ga12_Pathway 36 -1.2444
10 P53_UP 55 -1.2301
11 SA_CASPASE_CASCADE 31 -1.2147
12 Wnt_Signaling 79 -1.2121
13 fasPathway 60 -1.1990
14 EMT_DOWN 56 -1.1655
15 CR_CAM 143 -1.1651
16 cell_adhesion 245 -1.1628
17 NFKB_REDUCED 30 -1.1577
18 mRNA_processing 55 -1.1485
19 ST_MONOCYTE_AD_PATHWAY 39 -1.1485
20 GPCRs_Class_B_Secretin-like 28 -1.1401
21 GLUCOSE_DOWN 261 -1.1364
22 tnf_and_fas_network 33 -1.1302
23 ST_Fas_Signaling_Pathway 97 -1.1263
24 shh_lisa 33 -1.1164
25 intrinsicPathway 28 -1.1160
26 tgfbPathway 35 -1.0937
27 alkPathway 57 -1.0871
28 hdacPathway 45 -1.0860
29 41bbPathway 33 -1.0787
30 ST_Ga13_Pathway 54 -1.0367
  1. aSize refers to the number of included genes. NES, normalized enrichment scores