Target | Gene expression | Protein expression |
---|---|---|
IL-1β | ||
Degenerate discs | Proportion of samples ↑ and level ↑ (P < 0.05) | ↑ in NP and IAF (P < 0.05) |
Herniated discs | Proportion of samples ↑ (P < 0.05) | ↑ in NP and IAF (P < 0.05) |
IL-1 receptor | ||
Degenerate discs | Proportion of samples ↑ and level ↑ (P < 0.05) | ↑ in NP (P < 0.05) |
Herniated discs | Proportion of samples NC, level ↑ (P > 0.05) | ↑ in NP (P < 0.05) |
TNFα | ||
Degenerate discs | Proportion of samples ↑ (P < 0.05), level NC | ↑ in NP and IAF (P < 0.05) |
Herniated discs | Proportion of samples ↑ (P < 0.05), level NC | ↑ in NP (P < 0.05) |
TNF receptor | ||
Degenerate discs | Proportion of samples NC, level ↓ (P < 0.05) | ↓ in NP and IAF (P > 0.05) |
Herniated discs | Proportion of samples ↓ (P < 0.05), level NC | ↓ in NP (P > 0.05) |