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Table 3 Risk factors for hand bone loss in a multivariate linear regression model

From: Hand bone loss as an outcome measure in established rheumatoid arthritis: 2-year observational study comparing cortical and total bone loss

  DXA-BMD hand percentage change DXR-BMD hand percentage change DXR-MCI percentage change
  B (standard error) P value B (standard error) P value B (standard error) P value
Disease activity score including 28 joints 0.09 (0.25) 0.73 -0.47 (0.16) 0.003 -0.47 (0.18) 0.009
Disease duration <3 years -2.84 (0.88) 0.001 0.46 (0.55) 0.40 0.45 (0.63) 0.47
Baseline BMD (g/cm2)/MCI -9.70 (5.01) 0.05 -3.80 (2.51) 0.13 -5.79 (2.81) 0.04
Prednisolone during 2-year follow-up (no/yes) 0.44 (0.69) 0.53 -0.03 (0.43) 0.95 -0.41 (0.49) 0.40
Ever disease-modifying antirheumatic drug user (no/yes) -0.31 (0.90) 0.73 -0.58 (0.55) 0.30 -0.56 (0.63) 0.38
Ever antiresorptive osteoporosis treatment user (no/yes) 0.78 (0.70) 0.27 0.03 (0.42) 0.95 -0.05 (0.47) 0.91
R 2 0.11   0.05   0.06  
  1. B values are unstandardized coefficients. Age, gender, rheumatoid factor and the Modified Health Questionnaire were also tested, but did not influence the results. DXA, dual-energy X-ray absorptiometry; DXR, digital X-ray radiogrammetry; BMD, bone mineral density; MCI, metacarpal cortical index.