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Table 1 Details of the individuals and the tissue sources used in these studies (CVA = cerebrovascular accident ["stroke"])

From: Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an in situ zymographic and gene therapy study

Age (years) and sex Spinal level Score Reason excised/cause of death
Normal tissue: live patients    
   18 M L4/5 0 Spinal trauma
  L5/S1 1  
   24 M L3/4 1 Spinal trauma
   48 F L3/4 1 Spinal reconstruction for metastatic breast cancer
Normal tissue: cadaveric    
   59 F L3/4 1 Massive pulmonary embolism
   52 M L4/5 1 Myocardial infarction
   47 M L3/4 1 Road traffic accident
   72 M L3/4 1 Myocardial infarction
   64 M L5/S1 2 Myocardial infarction
   75 F L4/5 2 CVA
   47 F L4/5 3 Ovarian cancer
   58 M L4/5 3 Myocardial infarct
Degenerate tissue: live patients    
   51 M L4/5 7 Disc degeneration
   60 M L4/5 7 Disc degeneration
   25 M L4/5 8 Disc degeneration
   45 M L4/5 8 Disc degeneration
   48 M L4/5 8 Disc degeneration
   73 F L3/4 9 Disc degeneration
   61 M L5/S1 9 Disc degeneration
   45 F L5/S1 9 Disc degeneration
   53 M L4/5 10 Disc degeneration
   46 F L4/5 11 Data not available
Degenerate tissue: cadaveric    
   49 F L4/5 5 Data not available
   57 F L4/5 6 Myocardial infarction
   64 M L4/5 7 Myocardial infarction
   69 M L4/5 8 CVA
   47 F L3/4 8 Breast cancer
   76 M L4/5 9 CVA
   50 M L3/4 9 Myocardial infarction
   61 F L5/S1 10 Data not available
   28 M L4/5 11 Road traffic accident
   59 M L4/5 11 Myocardial infarction
  1. F, female; M, male.