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Table 1 Details of the individuals and the tissue sources used in these studies (CVA = cerebrovascular accident ["stroke"])

From: Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an in situ zymographic and gene therapy study

Age (years) and sex

Spinal level

Score

Reason excised/cause of death

Normal tissue: live patients

   

   18 M

L4/5

0

Spinal trauma

 

L5/S1

1

 

   24 M

L3/4

1

Spinal trauma

   48 F

L3/4

1

Spinal reconstruction for metastatic breast cancer

Normal tissue: cadaveric

   

   59 F

L3/4

1

Massive pulmonary embolism

   52 M

L4/5

1

Myocardial infarction

   47 M

L3/4

1

Road traffic accident

   72 M

L3/4

1

Myocardial infarction

   64 M

L5/S1

2

Myocardial infarction

   75 F

L4/5

2

CVA

   47 F

L4/5

3

Ovarian cancer

   58 M

L4/5

3

Myocardial infarct

Degenerate tissue: live patients

   

   51 M

L4/5

7

Disc degeneration

   60 M

L4/5

7

Disc degeneration

   25 M

L4/5

8

Disc degeneration

   45 M

L4/5

8

Disc degeneration

   48 M

L4/5

8

Disc degeneration

   73 F

L3/4

9

Disc degeneration

   61 M

L5/S1

9

Disc degeneration

   45 F

L5/S1

9

Disc degeneration

   53 M

L4/5

10

Disc degeneration

   46 F

L4/5

11

Data not available

Degenerate tissue: cadaveric

   

   49 F

L4/5

5

Data not available

   57 F

L4/5

6

Myocardial infarction

   64 M

L4/5

7

Myocardial infarction

   69 M

L4/5

8

CVA

   47 F

L3/4

8

Breast cancer

   76 M

L4/5

9

CVA

   50 M

L3/4

9

Myocardial infarction

   61 F

L5/S1

10

Data not available

   28 M

L4/5

11

Road traffic accident

   59 M

L4/5

11

Myocardial infarction

  1. F, female; M, male.