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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Skewed distribution of proinflammatory CD4+CD28nullT cells in rheumatoid arthritis

Figure 2

Skewed distribution of CD4+CD28null T cells in synovial fluid and peripheral blood. (a) Paired samples of synovial fluid (SF) and peripheral blood (PB) from 128 rheumatoid arthritis patients were compared for the frequency of CD4+CD28null T cells by flow cytometry. (b) Frequencies of CD4+CD28null T cells in SF tend to be higher in patients with large populations in PB. (c) Comparison of the frequency of CD4+CD28null T cells in SF from two different synovial compartments. Open circle, elbow; open squares, shoulder joints. Frequencies of CD4+CD28null T cells in (d) SF and (e) PB in patients seronegative and seropositive for human cytomegalovirus (HCMV). (f) Frequencies of CD4+CD28null T cells in paired PB and SF of patients seropositive for HCMV.

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