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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Insights into spatial configuration of a galactosylated epitope required to trigger arthritogenic T-cell receptors specific for the sugar moiety

Figure 3

Responses of anti-CII T hybridomas upon stimulation with chemically modified CII256–270 glycopeptides. Data are expressed as means of two to four individual experiments. Blocking effects of alterations (a) reaching the ε-primary amino group of Hyl264 or (b) strongly affecting the stereochemical position of sugar moiety. CII, collagen type II; CII256–270, immunodominant epitope of bovine type II collagen.

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