Figure 3

Responses of anti-CII T hybridomas upon stimulation with chemically modified CII256–270 glycopeptides. Data are expressed as means of two to four individual experiments. Blocking effects of alterations (a) reaching the ε-primary amino group of Hyl264 or (b) strongly affecting the stereochemical position of sugar moiety. CII, collagen type II; CII256–270, immunodominant epitope of bovine type II collagen.