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Table 1 Serum paraproteins in the case–control study of 74 age-matched and connective tissue disease (CTD) diagnosis-matched women with and without silicone implants

From: Serum proteins and paraproteins in women with silicone implants and connective tissue disease: a case–control study

 

Silicone implant

 

Yes (Group 1)

No (Group 2)

Age (years)a

49.9 ± 8.7

49.8 ± 8.4

Number of women with paraprotein band(s)/totalb

7/74 (9.5%)

4/74 (5.4%)

Number of women with paraprotein band(s) according to primary CTD diagnosis

   Unexplained polyarthritis

0/1 (0%)

0/1 (0%)

   Systemic sclerosis

1/10 (10%)

0/10 (0%)

   Systemic lupus erythematosus

0/1 (0%)

0/0 (0%)

   Polymyositis/dermatomyositis

1/13 (4%)

2/14 (4%)

   Undifferentiated CTD

4/39 (13%)

2/39 (5%)

   Fibromyalgia syndrome

1/10 (0%)

0/10 (10%)

Type of paraprotein band(s)c

  

   IgG(κ)

4

5

   IgG(λ)

1

1

   IgM(κ)

0

0

   IgM(λ)

2

1

  1. aPresented as the mean ± standard deviation, no significant difference by paired t test (P = 0.82). bNo significant differences between Groups 1 and 2 using the McNemar test (P = 0.55). cOne woman with dermatomyositis had two IgG(κ) and one IgG(λ) bands, whereas a patient with polymyositis had both IgG(κ) and IgM(λ) bands.