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Figure 6 | Arthritis Research & Therapy

Figure 6

From: IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats

Figure 6

Variation in degree of inflammation of rat paws after treatment with vehicle or IL-23 blockade. (a–c) Photographs showing paws of rats with collagen-induced arthritis (CIA) that were treated with vehicle or anti-IL-23 antibody on day 21. (a) Control rats. (b) Rats with CIA that were treated with vehicle. (c) Rats with CIA that were treated with anti-IL-23 antibody (3.0 μg) from day 14. (d–f) Slides stained with hematoxylin and eosin representing synovial tissues obtained from right paws on day 28. (d) Control rats. (e) Rats with CIA that were treated with vehicle. (f) Rats with CIA that were treated with anti-IL-23 antibody (3.0 μg) from day 14. Original magnification ×100.

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Arthritis Research & Therapy

ISSN: 1478-6362

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