Skip to main content

Table 3 Stratified analysis of rs729749 in men

From: A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity

Antibody status

Case/control

Genotypes

P

  

CC

CT

TT

 

RF positive

Case

0.68 (169)

0.29 (71)

0.03 (7)

0.0713

 

Control

0.58 (170)

0.37 (108)

0.04 (11)

 

RF negative

Case

0.71 (87)

0.20 (24)

0.09 (11)

0.0002

 

Control

0.57 (141)

0.40 (98)

0.04 (9)

 

Anti-CCP positive

Case

0.69 (159)

0.28 (63)

0.03 (7)

0.0398

 

Control

0.59 (167)

0.38 (107)

0.04 (11)

 

Anti-CCP negative

Case

0.70 (97)

0.22 (31)

0.08 (11)

0.0032

 

Control

0.59 (167)

0.38 (107)

0.04 (11)

 
  1. CCP, cyclic citrullinated peptide; RF, rheumatoid factor. Values indicate the genotype frequencies and number (in brackets).