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Table 4 Logistic regression analysis of rs729749 in cases stratified for autoantibody status

From: A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity

Status Subgroup Genotype CT versus CC Genotype TT versus CC
   OR 95% CI P OR 95% CI P
All All 0.80 0.66 to 0.97 0.02 1.04 0.67 to 1.62 0.86
  Women 0.94 0.75 to 1.17 0.56 1.01 0.60 to 1.71 0.97
  Men 0.50 0.35 to 0.73 0.0002 1.20 0.52 to 2.81 0.67
RF positive All 0.85 0.69 to 1.04 0.12 0.92 0.56 to 1.53 0.76
  Women 0.96 0.75 to 1.23 0.74 1.03 0.58 to 1.84 0.92
  Men 0.59 0.39 to 0.88 0.009 0.74 0.26 to 2.12 0.58
RF negative All 0.70 0.54 to 0.90 0.006 1.24 0.71 to 2.14 0.45
  Women 0.88 0.65 to 1.18 0.39 0.94 0.47 to 1.90 0.87
  Men 0.34 0.20 to 0.60 0.0001 2.03 0.88 to 5.29 0.15
Anti-CCP positive All 0.86 0.70 to 1.07 0.17 1.01 0.61 to 1.71 0.98
  Women 1.02 0.80 to 1.31 0.88 1.12 0.63 to 2.00 0.70
  Men 0.54 0.36 to 0.83 0.003 0.79 0.28 to 2.24 0.65
Anti-CCP negative All 0.69 0.54 to 0.89 0.004 1.07 0.62 to 1.84 0.82
  Women 0.82 0.61 to 1.10 0.19 0.86 0.43 to 1.73 0.67
  Men 0.4 0.2 to 0.7 0.0004 1.8 0.7 to 4.6 0.26
  1. CCP, cyclic citrullinated peptide; CI, confidence interval; OR, odds ratio; RF, rheumatoid factor.