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Table 6 Genetic models of rs729749 in RF negative males

From: A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity

Model

Frequency of risk variant

OR

95% CI

P

 

Cases

Controls

   

CC + TT versus CT

0.80

0.60

2.67

1.60 to 4.46

0.0002

CC versus CT

0.71

0.57

2.52

1.50 to 4.24

0.0004

TT versus CT

0.09

0.04

4.99

1.86 to 13.4

0.0016

CC versus CT + TT

0.71

0.57

1.89

1.18 to 3.01

0.0088

TT versus CC + CT

0.09

0.04

2.63

1.06 to 6.53

0.0476

  1. CI, confidence interval; OR, odds ratio; RF, rheumatoid factor.